The physical and chemical properties of dichloropropane

Chemical name: 1,2-Dichloropropane

Harmful ingredients content CAS No.

1,2-dichloropropane ≥80.0% 78-87-5

Part III: Overview of Hazards

Hazard category: Class 3.2 flammable liquid with flash point.

Invasion route: skin contact, inhalation, ingestion, eye contact.

Health hazards: Harmful to the body after inhalation, ingestion or absorption through the skin. 1,2-Dichloropropane has an inhibitory effect on the central nervous system; it can cause dry skin, desquamation and chapped skin; it has a stimulating effect on mucous membranes; it can cause fatty degeneration of liver, kidney and myocardium. Skin contact: Take off contaminated clothing and rinse thoroughly with soap and water.

Environmental hazards: The sealing of this product has no impact on the environment.

Combustion and explosion hazard: This product is flammable in case of open flame and may cause an explosion in a closed container.

Part 4: First aid measures

Skin contact: Take off contaminated clothing and rinse skin thoroughly with clean water.

Eye contact: Lift the eyelids and rinse with running water or normal saline. Seek medical attention.

Inhalation: Leave the scene quickly to a place with fresh air. Keep the airway unobstructed. If breathing is difficult, give oxygen. If breathing stops, give artificial respiration immediately. Seek medical attention.

Ingestion: gastric lavage. Seek medical attention.

Part V: Fire Fighting Measures

Hazardous characteristics: It is flammable, and its steam and air can form an explosive mixture, which can cause combustion and explosion when exposed to open flames and high heat energy. Decomposed by high heat to produce toxic corrosive fumes. It reacts with oxidants, and can easily cause combustion when exposed to open flames and high heat, and emit toxic gases. Its steam is heavier than air, and can spread to a considerable distance at a lower place, and will ignite back when it encounters a fire source.

Hazardous combustion products: carbon monoxide, carbon dioxide, hydrogen chloride, phosgene.

Extinguishing method: Spray water to cool the container. If possible, move the container from the fire scene to an open place. If the container in the fire scene has changed color or produces sound from the safety relief device, it must be evacuated immediately.

Extinguishing agent: foam, dry powder, carbon dioxide, sand, water mist.

Precautions for fire extinguishing: Water jet extinguishing is invalid.

Part VI: Emergency Response to Leakage

Emergency treatment: Quickly evacuate personnel from the leaked contaminated area to a safe area, isolate them, and strictly restrict access. Cut off the fire source. It is recommended that emergency personnel wear self-contained positive pressure breathing apparatus. Cut off the source of leakage as much as possible. Prevent entry into restricted spaces such as sewers and flood drains. Small leakage: Use sand or other non-combustible materials to absorb or absorb. It can also be washed with a large amount of water, and the washing water is diluted and put into the waste water system. A large number of leaks: build a dike or dig a pit for storage. Cover with foam to reduce steam disasters. Use explosion-proof pump to transfer to tank truck or special collector, recycle or transport to waste disposal site for disposal.

Part 7: Handling and storage

Operation precautions: airtight operation, local exhaust. Operators must undergo special training and strictly abide by the operating procedures. It is recommended that operators wear filter-type gas masks (half masks), chemical safety glasses, anti-static overalls, and rubber oil-resistant gloves. Keep away from fire and heat sources, and smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment. Prevent steam from leaking into the workplace air. During filling, the flow rate should be controlled, and there should be a grounding device to prevent static electricity from accumulating. When handling, load and unload with care to prevent damage to packaging and containers. Equipped with corresponding types and quantities of fire-fighting equipment and leakage emergency treatment equipment. Empty containers may be harmful residues.

Storage precautions: Store in a cool, ventilated warehouse. Keep away from fire and heat sources. The storage temperature should not exceed 30°C. Keep the container tightly closed. It should be stored separately from oxidants, acids, alkalis, and edible chemicals, and avoid mixed storage. Use explosion-proof lighting and ventilation facilities. It is forbidden to use mechanical equipment and tools that are prone to sparks. The storage area should be equipped with leakage emergency treatment equipment and suitable storage materials.

Part 8: Exposure Control/Personal Protection

Monitoring method: Gas chromatography

Engineering control: airtight operation, local exhaust. Provide safety shower and eyewash equipment.

Respiratory system protection: When the concentration in the air exceeds the standard, it is recommended to wear a filter gas mask (half mask). Wear an isolated respirator during emergency rescue or evacuation.

Eye protection: Wear chemical safety glasses.

Body protection: Wear work clothes, and no body contact with liquids

Hand protection: Wear rubber and oil-resistant gloves.

Part 9: Physical and Chemical Properties

Main ingredients: Content: Industrial grade ≥80.0%.

Appearance and properties: colorless or light yellow transparent liquid, with a odor similar to chloroform.

Melting point (℃): -80

boiling point (℃): 96.8

Relative density (water=1): 1.13 ～1.23

Relative vapor density (air=1): 3.9

Saturated vapor pressure (kPa): 5.33(19.4℃)

Heat of combustion (kJ/mol): 1542.8

Critical temperature (℃): 290

Critical pressure (MPa): 4.44

The logarithm of the octanol/water partition coefficient: Water% ≤ 0.1

Flash point (℃): -18～<23

Natural temperature (℃): 555

Lower explosion limit (V%): 3.4

Explosion limit (V%): 14.5

Solubility: insoluble in water, soluble in most organic solvents.

Main uses: paint, ink, used to prepare paint and ink. Dilute PUC adhesive

Part 10: Stability and Reactivity

Stability: Stable.

Incompatible materials: strong oxidizers, acids, alkalis, aluminum.

Conditions to avoid contact: Avoid heat, shock, and squeeze.

Polymerization hazard: it cannot happen.

Decomposition products: carbon monoxide, carbon dioxide, hydrogen chloride.

Part 11: Toxicological Information

"Acute toxicity: LD50: 680 mg/kg (rat oral); 2800 mg/kg (rat transdermal); LC50: 4050 mg/m3, 432 min (rat inhalation). Acute toxicity Inhalation of 40.5 g/m3 can cause deep anesthesia in cats, rabbits and guinea pigs, and cause quadriplegia in cats. It has a deeper and longer anesthesia effect than inhalation of carbon tetrachloride or chloroform at the same concentration, but the recovery is faster, and it can affect liver function. The damage is lighter than carbon tetrachloride. The mouse anesthesia concentration is about 20.25 g/m3.

Subacute and chronic toxicity: monkey inhaled 0.22 g/m3, 7 h/d, 5 d/week, 125 times, asymptomatic; 4.11 g/m3, 7 h/d, 5 d/week, 25-50 times, death The rate is higher. The sensitivity of small animals to 1,2-dichloropropane is higher than that of large animals. Autopsy of chronic animal poisoning showed enlarged heart, pulmonary congestion and edema, fatty infiltration of myocardium and liver, fatty nephropathy, and adrenal lipid accumulation.

Irritation: Rabbit eyes: 63mg, severe irritation. Rabbit percutaneous open irritation test: 625mg, mild irritation.

Sensitization: Not available

Mutagenicity: Occupational exposure causes chromosomal aberrations in human peripheral blood lymphocytes.

Teratogenicity: No data

Carcinogenicity: IARC Carcinogenicity Comment: Positive in animals, suspicious in humans.

Part 12: Ecological Information

Ecotoxicity: Not available

Biodegradability: No data

Non-biodegradability: No data

Bioaccumulation or bioaccumulation: No data

Other harmful effects: This substance has serious harm to the environment. Special attention should be paid to the pollution of water bodies, and special attention should be paid to fish and animals.

Part 13: Disposal

Waste nature: hazardous waste

Waste disposal method: Dispose by incineration. After being mixed with fuel, it is incinerated. The hydrogen halide discharged from the incinerator is removed by an acid scrubber.

Abandonment notes:

1. It is prohibited to accumulate combustible waste products in the storage area of ​​chemical hazardous materials.

2. Leaked and leaking dangerous goods packaging containers are not allowed to move to a safe area.

3. According to the characteristics of chemical dangerous goods, use chemical and physical methods to dispose of waste products, and shall not discard them at will to pollute the environment.

Part 14: Transportation Information

Dangerous Goods Number: 32036

UN Number: 1279

Packaging mark: Each package should have the name, factory address, product grade batch number, production date, serial number, and net weight mark. There are 190 “flammable liquids” and “drugs” marks in white iron drums, with a net weight of 240 kg.

Packing category: Class Ⅱ.

Packing method: ordinary wooden box outside the ampoule; ordinary wooden box outside the screw-top glass bottle, iron cap crimped glass bottle, plastic bottle or metal barrel (can).

Transportation precautions: During railway transportation, it should be installed strictly in accordance with the dangerous goods distribution table in the "Rules for the Transport of Dangerous Goods" of the Ministry of Railways. Transport vehicles should be equipped with corresponding types and quantities of fire-fighting equipment and leakage emergency treatment equipment during transportation. It is best to transport sooner or later in summer. The tank (tank) truck used for transportation should have a grounding chain, and a hole partition can be set in the tank to reduce vibration and static electricity. Mixed shipment and transportation with oxidants, acids, alkalis, edible chemicals, etc. are strictly prohibited. Avoid exposure to the sun, rain, and high temperature during transportation. Stay away from fire, heat sources, and high-temperature areas during stopovers. The exhaust pipe of the vehicle carrying the item must be equipped with a fire arrester, and it is prohibited to use mechanical equipment and tools that are prone to sparks for loading and unloading. When transporting by road, follow the prescribed route and do not stop in residential or densely populated areas. It is forbidden to drop off during railway transportation. It is strictly forbidden to transport in bulk by wooden ships or cement ships.